Publikationen

2023

Ettich J, Wittich C, Moll JM, Behnke K, Floss DM, Reiners J, Christmann A, Lang PA, Smits SHJ, Kolmar H, Scheller J (2023) Respiratory syncytial virus-approved mAb Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors. J Biol Chem 299(11):105270

Offen N, Filatova A, Nuber UA (2023)Enrichment of FGF8-expressing cells from neurally induced human pluripotent stem cell cultures. Stem Cell Reports https://doi.org/10.1016/j.stemcr.2023.10.007

Riahi K, Dirba I, Ablets Y, Filatova A, Sultana SN, Adabifiroozjaei, Molina-Luna L, Nuber U, Gutfleisch (2023) Surfactant-driven optimization of iron-based nanoparticle synthesis: a study on magnetic hyperthermia and endothelial cell uptake. Nanoscale Adv 5:5859-5869

Kraus L, Duchardt-Ferner E, Bräuchle E, Fürbacher S, Kelvin D, Marx H, Boussebayle A, Maurer LM, Bofill-Bosch C, Wöhnert J, Suess B (2023) Development of a novel tobramycin dependent riboswitch Nucleic Acids Res. 2023 Oct 4:gkad767

Schoenfeld K, Harwardt J, Habermann J, Elter A, Kolmar H (2023) Conditional activation of an anti-IgM antibody-drug conjugate for precise B cell lymphoma targeting. Front Immunol 14:1258700

Bitsch P, Baum ES, Beltrán Hernández I, Bitsch S, Harwood J, Oliveira S, Kolmar H (2023) Penetration of Nanobody-Dextran Polymer Conjugates through Tumor Spheroids. Pharmaceutics 15(10):2374

Lerma Romera JA, Meyners C, Rupp N, Hausch F, Kolmar H (2023) A protein engineering approach towards understanding FKBP51 conformational dynamics and mechanisms of ligand binding. Protein Eng Des Sel doi: 10.1093/protein/gzad014

Kemp P, weber W, Desczyk C, Kaufmann M, Panthel J, Wörmann J, Stein V (2023) Dissecting the Permeability of the Escherichia coli Cell Envelope to a Small Molecule Using Tailored Intensiometric Fluorescent Protein Sensors ACS Omega 42:39562–39569

Sinzger-D’Angelo M, Startceva S& Koeppl H (2023) Bye bye, linearity, bye: quantification of the mean for linear CRNs in a random environment Journal of Mathematical Biology 87:43

Minagawa J, Dann M (2023) Extracellular CahB1 from Sodalinema gerasimenkoae IPPAS B-353 Acts as a Functional Carboxysomal β-Carbonic Anhydrase in Synechocystis sp. PCC6803 Plants 12(2):265

Engelmann N, Schwarz T, Kubaczka E, Hochberger C, Koeppl H (2023) Context-Aware Technology Mapping in Genetic Design Automation ACS Synthetic Biology, S. 446-459:2161-5063

Fritschen A, Blaeser A (2023) Biosynthetic, biomimetic, and self-assembled vascularized Organ-on-a-Chip systems Biomaterials, 268, Darmstadt, Elsevier, Universitäts- und Landesbibliothek Darmstadt ISSN 1878-5905

Fritschen A, Acedo Mestre M, Scholpp S, Blaeser A (2023) Influence of the physico-chemical bioink composition on the printability and cell biological properties in 3D-bioprinting of a liver tumor cell line Frontiers in Bioengineering and Biotechnology 11

Gouveia MG, Wesseler JP, Ramaekers J, Weder C, Scholten PBV, Bruns N (2023) Polymersome-based protein drug delivery – quo vadis? Chemical Society Reviews . 52(2)728-778:51

Redondo A, Bast LK, Djeghdi K, Airoldi M, Jang D, Korley LTJ, Steiner U, Bruns N, Gunkel I (2023) Rendering polyurethane hydrophilic for efficient cellulose reinforcement in melt-spun nanocomposite fibers Advanced Materials Interfaces. 10, 9, 9 2201979

Wesseler JP, Cameron GM, Cormack PAG, Bruns N (2023) Donor-acceptor Stenhouse adduct functionalised polymer microspheres (wird in neuem Tab geöffnet) Polymer Chemistry. 14(13)1456-1468 :13

Belluati, A, Harley I, Lieberwirth I, Bruns N (2023) An outer membrane‐inspired polymer coating protects and endows Escherichia coli with novel functionalities (wird in neuem Tab geöffnet) Small 8:2303384

Russell S, Bruns N (2023) Encapsulation of fragrances in micro‐ and nano‐capsules, polymeric micelles, and polymersomes (wird in neuem Tab geöffnet) Macromolecular Rapid Communications. 15:2300120

Ritzmann D, Jahn M, Heck S, Jung C, Cesetti T, Couturier N, Rudolf R, Reuscher N, Buerger C, Rauh O, Fauth T (2023) The Ca2+ channel TRPV4 is dispensable for Ca2+ influx and cell volume regulation during hypotonic stress response in human keratinocyte cell lines. Cell Calcium 111:102715

Poggio E, Vallese F, Hartel AJW, Morgenstern TJ, Kanner SA, Rauh O, Giamogante F, Barazzuol L, Shepard KL, Colecraft HM, Clarke OB, Brini M, Calì T (2023) Perturbation of the host cell Ca2+ homeostasis and ER-mitochondria contact sites by the SARS-CoV-2 structural proteins E and M Cell Death & Disease 14(297)

Höler S, Degreif D, Stix F, Yang S, Gao S, Nagel G, Moroni A, Thiel G, Bertl A, Rauh O (2023) Tailoring baker’s yeast Saccharomyces cerevisiae for functional testing of channelrhodopsin. PLoS ONE 18(4):e0280711

Bohn S, Hexemer L, Huang Z, Strohmaier L, Lenhardt S, Legewie S, Loewer A (2023) State- and stimulus-specific dynamics of SMAD signaling determine fate decisions in individual cells. Proc Natl Acad Sci U S A. 120(10):e2210891120

Konrath, F, Loewer, A & Wolf, J (2023) Resolving Crosstalk Between Signaling Pathways Using Mathematical Modeling and Time-Resolved Single Cell Data. Methods Mol. Biol. (Clifton, NJ) 2634:267–284

Cichos S, Schätzlein E, Wiesmann-Imilowski N, Blaeser A, Henrich D, Frank J, Drees P, Gercek E, Ritz U (2023) A new 3D-printed polylactic acid-bioglass composite for bone tissue engineering induces angiogenesis in vitro and in ovo. Int J Bioprint. 11;9(5):751

Klein T, Funke F, Rossbach O, Lehmann G, Vockenhuber M, Medenbach J, Suess B, Meister G, Babinger P (2023) Investigating the Prevalence of RNA-Binding Metabolic Enzymes in E. coli. Int J Mol Sci. 16;24(14):11536

Kelvin D, Suess B (2023) Tapping the potential of synthetic riboswitches: reviewing the versatility of the tetracycline aptamer. RNA Biol. 20(1):457-468

Krumbach JH, Bauer D, Sharifzadeh AS, Saponaro A, Lautenschläger R, Lange K, Rauh O, DiFrancesco D, Moroni A, Thiel G, Hamacher K (2023) Alkali metal cations modulate the geometry of different binding sites in HCN4 selectivity filter for permeation or block. J Gen Physiol. 2;155(10):e202313364

Lipinski B, Unmuth L, Arras P, Becker S, Bauer C, Toleikis L, Krah S, Doerner A, Yanakieva D, Boje AS, Klausz K, Peipp M, Siegmund V, Evers A, Kolmar H, Pekar L, Zielonka S (2023) Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition. MAbs. 15(1):2236265

Oliviero C, Hinz SC, Grzeschik J, Hock B, Kolmar H, Hagens G (2023) Cell Line Development Using Targeted Gene Integration into MAR-Rich Landing Pads for Stable Expression of Transgenes. Methods Mol Biol 343-359

Carrara SC, Bogen JP, Fiebig D, Grzeschik J, Hock B, Kolmar H (2023) Bulk Reformatting of Antibody Fragments Displayed on the Surface of Yeast Cells to Final IgG Format for Mammalian Production. Methods Mol Biol 2681:291-311

Lerma Romero JA, Kolmar H (2023) Accessing Transient Binding Pockets by Protein Engineering and Yeast Surface Display Screening. Methods Mol Biol 2681:249-274

Yanakieva D, Vollmer L, Kumar S, Becker S, Toleikis L, Pekar L, Kolmar H, Zielonka S, Krah S (2023) One-Pot Droplet RT-OE-PCR for the Generation of Natively Paired Antibody Immune Libraries. Methods Mol Biol 2681:213-229

Deutscher R, Karagöz MS, Purder PL, Kolos J, Meyners C, Sugiarto WO, Krajczy P, Tebbe F, Geiger T, Ünal C, Hellmich U, Steinert M, Felix Hausch F (2023) Bicyclic FKBP ligands inhibit Legionella pneumophila infection by LpMipdependent and LpMip independent mechanisms ChemBioChem e202300442

Knaup FH, Meyners C, Sugiarto WO, Wedel S, Springer M, Walz C, Geiger TM, Schmidt M, Sisignano M, Hausch F (2023) Structure-Based Discovery of a New Selectivity-Enabling Motif for the FK506-Binding Protein 51 Journal of Medical Chemistry 66(8):5965–5980

Harwardt J, Carrara SC, Bogen JP, Schoenfeld K, Grzeschik J, Hock B, Kolmar H (2023) Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody Front Immunol 14:1170042

Kunzmann P, Müller TD, Greil M, Krumbach JH, Anter JM, Bauer D, Islam F, Hamacher K (2023) Biotite: New tools for a versatile Python bioinformatics library BMC Bioinformatics 24:236

Mikolei JJ, Stanzel M, Pardehkorram R, Lehn R, Ceolin M, Andrieu-Brunsen A (2023) Fluid Flow Control in Cotton Threads with MesoporousSilica Coatings Advanced Material Interfaces 10:2300211

Mikolei JJ, Richter D, Pardehkhorram R, Helbrecht C, Schabel S, Meckel T, Biesalski M, Ceolind M, Andrieu-Brunsen A (2023) Nanoscale pores introduced into paper via mesoporous silica coatings using sol–gel chemistry Nanoscale 15:9094-9105

Despot L, Andrieu-Brunsen A (2023) Effects of the Polymer Amount and pH on Proton Transport in Mesopores Adv. Mater. Interfaces 2202456

Förster C, Lehn R, Saritas EM, Andrieu-Brunsen A (2023) Laser Writing of Block-Copolymer Images into Mesopores Using SBDC-Initiated Visible-Light-Induced Polymerization Angew Chem e202217806

Varol HS, Förster C, Andrieu-Brunsen A (2023) Ligand-Binding Mediated Gradual Ionic Transport in Nanopores,Adv Mater Interfaces 2201902

Förster C, Lehn R, Andrieu-Brunsen A (2023) Automated Multi- and Block-Copolymer Writing in Mesoporous Films Using Visible-Light PET-RAFT and a Microscope Small 2207762

C. Förster, A. Andrieu-Brunsen (2023) Recent developments in visible light induced polymerization towards its application to nanopores, Chem. Commun. 59:1554 – 1568

Scheidt J, Diener A, Maiworm M, Müller K-R, Findeisen R, Driessens K, Tautz FS, Wagner C (2023) Concept for the Real-Time Monitoring of Molecular Configurations during Manipulation with a Scanning Probe Microscope Journal of Physical Chemistry C, ACS Publications, ISSN 1932-7447

Pohlodek J, Alsmeier H, Morabito B, Schlauch C, Savchenko A, Findeisen R (2023) Stochastic Model Predictive Control Utilizing Bayesian Neural Networks. American Control Conference (ACC 2023), pp. 603-608, IEEE, 2023 American Control Conference, San Diego, USA, 31.05. – 02.06.2023, ISBN 979-8-3503-2806-6

Schurig R, Himmel A, Mešanović A, Braatz RD, Findeisen R (2023) Estimating Parameter Regions for Structured Parameter Tuning via Reduced Order Subsystem Models. American Control Conference (ACC 2023), pp. 3809-3814, IEEE, 2023 American Control Conference, San Diego, USA, 31.05.-02.06.2023, ISBN 979-8-3503-2806-6

Schurig R, Himmel A, Findeisen R (2023) Towards Grassmannian Dimensionality Reduction in MPC. IEEE Control Systems Letters, IEEE, e-ISSN 2475-1456

Schaeffer J, Gasper P, Garcia-Tamayo E, Gasper R, Adachi M, Gaviria-Cardona JP, Montoya-Bedoya S, Bhutani A, Schiek A, Goodall R, Findeisen R, Braatz RD, Engelke S (2023) Machine Learning Benchmarks for the Classification of Equivalent Circuit Models from Electrochemical Impedance Spectra. Journal of The Electrochemical Society, 170(6):1-14

Peters S, PJ, Findeisen R (2023) Quantifying uncertainties along the automated driving stack. ATZ worldwide, pp. 62-65, Springer, ISSN 0001-2785, e-ISSN 2192-9076

Bethge J, Pfefferkorn M, Rose A, Peters J, Findeisen R (2023) Model Predictive Control with Gaussian-Process-Supported Dynamical Constraints for Autonomous Vehicles. Electrical Engineering and Systems Science, arXiv

Matschek J, Bethge J, Findeisen R (2023) Safe Machine-Learning-supported Model Predictive Force and Motion Control in Robotics. Robotics, arXiv

Wan Y, Shen DE, Lucia S, Findeisen R, Braatz RD (2023) A Polynomial Chaos Approach to Robust H_infinity Static Output-Feedback Control with Bounded Truncation Error. IEEE Transactions on Automatic Control, 68 (1), pp. 470-477, IEEE, ISSN 0018-9286

Kögel M, Ibrahim M, Kallies C, Findeisen R (2023) Safe hierarchical model predictive control and planning for autonomous systems. International Journal of Robust and Nonlinear Control, pp. 1-19, John Wiley & Sons Ltd., ISSN 1049-8923, e-ISSN 1099-1239

Shi Z, Chen H, Yu S, Findeisen R, Guo H (2023) Nonlinear model predictive control for autonomous vehicle drifting. International Journal of Robust and Nonlinear Control, pp. 1-20, John Wiley and Sons Ltd

Domes R, Frosch T (2023) Investigations on the Novel Antimalarial Ferroquine in Biomimetic Solutions Using Deep UV Resonance Raman Spectroscopy and Density Functional Theory Analytical Chemistry 95(19):7630-7639

Wolf S, Popp J, Frosch T (2023) Multifocal hyperspectral Raman imaging setup for multi-well plates Sensors and Actuators B: Chemical 375(132949):3

Domes C, Popp J, Hagel S, Pletz MW, Frosch T (2023) Towards therapeutic drug monitoring of antibiotic levels–analyzing the pharmacokinetics of levofloxacin using DUV-resonance Raman spectroscopy Analyst 148:3057-3064

Cervera J, Ramirez P, Nasir S, Ali M, Ensinger W, Z. Siwy S, Mafe S (2023) Cation pumping against a concentration gradient in conical nanopores characterized by load capacitors Bioelectrochemistry 152:108445

2022

Kramat J, Suess B (2022) Efficient Method to Identify Synthetic Riboswitches Using RNA-Based Capture-SELEX Combined with In Vivo Screening Methods Mol Biol. 2022;2518:157-177

Fernengel B, Drossel B (2022) Obtaining the long-term behavior of master equations with finite state space from the structure of the associated state transition network, J. Phys. A: Mathematical and Theoretical 55, 115201.

Pardehkhorram R, Andrieu-Brunsen A (2022) Pushing the limits of nanopore transport performance by polymer functionalization Chem. Commun., invited Feature Article, 58, 5188-5204

Schneider S, Brodrecht M, Breitzke H, Wissel T, Buntkowsky G, Varol HS, Brilmayer R, Andrieu-Brunsen A Vogel M (2022) Local and diffusive dynamics of LiCl aqueous solutions in pristine and modified silica nanopores. J Chem Phys in press

Rauh O, Opper J, Sturm M, Drexler N, Scheub DD, Hansen UP, Thiel G, Schroeder I (2022) Role of Ion Distribution and Energy Barriers for Concerted Motion of Subunits in Selectivity Filter Gating of a K+ Channel J of Mol Biol 434(9):167522

Rauh O, Schroeder I and Thiel G (2022) Plasticity of gating in pore-only potassium channels (wird in neuem Tab geöffnet). Biophys. J. 121(3)

Espinel-Ríos S, Bettenbrock K, Klamt, S, and Findeisen R (2022) Maximizing batch fermentation efficiency by constrained model‐based optimization and predictive control of adenosine triphosphate turnover. AIChE J. 68.

Sheludko YV, Gerasymenko IM, Herrmann FJ, Warzecha H (2022) Evaluation of biotransformation capacity of transplastomic plants and hairy roots of Nicotiana tabacum expressing human cytochrome P450 2D6 Transgenic Research volume 31, pages 351–368

Bauer D, Wissmann J, Moroni A, Thiel G, Hamacher K (2022) Weak Cation Selectivity in HCN Channels Results From K+-Mediated Release of Na+ From Selectivity Filter Binding Sites Function, Volume 3, Issue 3, 2022, zqac019

Weber W, Roeder M, Probanowski T, Yang J, Abujubara H, Koeppl H, Tietze A, Stein V (2022) Functional Nanopore Screen: A Versatile High-Throughput Assay to Study and Engineer Protein Nanopores in Escherichia coli ACS Synth. Biol. 2022, 11, 6, 2070–2079

Lindner N, Blaeser A (2022) Scalable Biofabrication: A Perspective on the Current State and Future Potentials of Process Automation in 3D-Bioprinting Applications Frontiers in Bioengineering and Biotechnology, 10, Frontiers, e-ISSN 2296-4185,

Caronna F, Glimpel N, Paar G, Thomas Gries, Blaeser A, Do K, Dolan EB, Ronan W (2022) Manufacturing, characterization, and degradation of a poly (lactic acid) warp-knitted spacer fabric scaffold as a candidate for tissue engineering applications Biomaterials Science

Karakaya E, Bider F, Frank A, Teßmar J, Schöbel L, Forster L, Schrüfer S, Schmidt H, Schubert DW, Blaeser A, Boccaccini AR, Detsch R (2022) Targeted Printing of Cells: Evaluation of ADA-PEG Bioinks for Drop on Demand Approaches Gels 8 (4), 206

Salg GA, Poisel E, Neulinger-Munoz M, Gerhardus J, Cebulla D, Bludszuweit-Philipp C, Vieira V, Nickel F, Herr I, Blaeser A, Giese NA, Hackert T, Kenngott HG (2022) Toward 3D-bioprinting of an endocrine pancreas: A building-block concept for bioartificial insulin-secreting tissue Journal of Tissue Engineering 13, 20417314221091033

Brumm P, Fritschen A, Doß L, Dörsam E, Blaeser A (2022) Fabrication of biomimetic networks using viscous fingering in flexographic printing Biomedical Materials 17 (4), 045012

Schätzlein E, Kicker C, Söhling N, Ritz U, Neijhoft J,Henrich D, Frank J, Marzi I, Blaeser A (2022) 3D-Printed PLA-Bioglass Scaffolds with Controllable Calcium Release and MSC Adhesion for Bone Tissue Engineering Polymers 14 (12), 2389

Fritschen A, Bell AK, Königstein I, Stühn L, Stark RW, Blaeser A (2022) Investigation and comparison of resin materials in transparent DLP-printing for application in cell culture and organs-on-a-chip Biomaterial Science

Bauer B, Emonts C, Bonten L, Annan R, Merkord F, Vad T, Idrissi A, Gries T, Blaeser A (2022) Melt-Spun, Cross-Section Modified Polycaprolactone Fibers for Use in Tendon and Ligament Tissue Engineering Fibers 10(3):23

Wollschläger JO, Maatz R, Albrecht FB, Klatt A, Heine S, Blaeser (2022) Scaffolds for Cultured Meat on the Basis of Polysaccharide Hydrogels Enriched with Plant-Based Proteins Gels 8(2):94

Rocabert E, Muench F, Fries M, Beckmann B, Loewe K, Vieyra H, Katter M, Barcza A, Ensinger W, Gutfleisch O (2022) Electrochemical corrosion study of La (Fe11, 6-xSix1, 4Mnx) H1, 5 in diverse chemical environments Electrachimica Acta, Vol. 434, 141200

Bräuer P, Muench F, Stojkovikj S, Gupta S, Mayer M, Ensinger W, Roth C, El-Nagar GA (2022)Shape-Controlled Electroless Plating of Hetero-Nanostructures: AgCu-and AgNi-Decorated Ag Nanoplates on Carbon Fibers as Catalysts for the Oxygen Evolution ACS Appl. Nano Mater. 5, 8 360, 119592

Perez-Grau J, Cervera J, Nasir S, Mubarak A, Ensinger W, Ramirez P, Mafe S (2022) Additivity of ionic currents in mixed electrolyte solutions and confined geometries Journal of Molecular Liquids, Vol. 360, 119592

Ramirez P, Cervera J, Manzanares J, Nasir S, Mubarak A, Ensinger W, Mafe S (2022) Electrical conductance of conical nanopores: symmetric and assymmetric salts and their mixtures Journal of Chemical Physics, Vol. 157, 144702

Amin KM, Krois K, Muench F, Etzold BJM, Ensinger W (2022) Hierarchical pipe cactus-like Ni/NiCo-LDH core–shell nanotube networks as a self-supported battery-type electrode for supercapacitors with high volumetric energy density Journal of Materials Chemistry A, 2022, pp. 1-16. Royal Society of Chemistry, ISSN 2050-7488

Groeb M, Hageluken L, Groeb J, Ensinger W (2022) Experimental Analysis of Ductile Cutting Regime in Face Milling of Sintered Silicon Carbide Materials 15, 7 2409

Hossain UH, Jantsen G, Muench F, Kunz U, Ensinger W (2022) Increasing the structural and compositional diversity of ion-track templated 1D nanostructures through multistep etching, plastic deformation, and deposition Nanotechnology 33, 24 (2022) 245603

Nowroozi MA, Waidha AI, Jacob M, van Aken PA, Predel F, Ensinger W, Clemens O (2022) Towards Recycling of LLZO Solid Electrolyte Exemplarily Performed on LFP/LLZO/LTO Cells ChemistryOpen 11, 3 202100274

Amin KM, Boettcher T, Scheuerlein MC, Ensinger W (2022) Exotemplate-based Fabrication of 1-dimensional Hybrid Nanostructures for Catalysis and Sensing (wird in neuem Tab geöffnet) in Proceedings of the 7th World Congress on Recent Advances in Nanotechnology (RAN'22), ICNNFC 173, Int. ASET Inc., Ottawa 2022

Rubab A, Baig N, Sher M, Ali M, Ul-Hamid A, Jabeen N, Khan LU, Sohail M (2022) Synthesis and Characterization of a Carbon-Supported Cobalt Nitride Nano-Catalyst ChemNanoMat 2022, 8, e202100428

Froehlich K, Scheuerlein MC, Nasir S, Ali M, Ensinger W (2022) Enhancement of heavy ion track-etching in polyimide membranes with organic solvents Nanotechnology 2021, Vol. 33, 045301

Haider MHA, Nasir S, Amin KM, Ali M, Ramirez P, Cervera J, Mafe S, Ensinger W (2022) Osmotic energy harvesting with soft-etched nanoporous polyimide membranes Materials Today Energy, Vol. 23 100909

Abbasi MA, Amin KM, Ali M, Zulqurnain Ali A, Atif M, Ensinger W, Khalid W (2022) Synergetic effect of adsorption-photocatalysis by GO-CeO2 nanocomposites for photodegradation of doxorubicin Journal of Environmental Chemical Engineering 10, 1 107078

Wolf S, Domes R, Merian A, Domes C, Frosch T (2022) Parallelized Raman Difference Spectroscopy for the Investigation of Chemical Interactions Analytical Chemistry 94 (29), 10346-10354 2

L Wang, W Zheng, F Vitale, X Zhang, X Li, Y Ji, Z Liu, O Ghaebi, CT Plass, Domes T, Frosch T, Soavi G, Wendler E, Zhang Y, Ronning C (2023) Wide‐Bandgap Double Perovskites with Multiple Longitudinal‐Optical Phonon ScatteringAdvanced Functional Materials 32 (22), 2111338 18 2022

Blohm A, Kumar S, Knebl A, Herrmann M, Küsel K, Popp J, Frosch T (2022) Activity and electron donor preference of two denitrifying bacterial strains identified by Raman gas spectroscopy Analytical and bioanalytical chemistry 414 (1), 601-611

2021

Winterstein L, Kukovetz K, Hansen U, Schroeder I, Van Etten JL, Moroni A, Thiel G, Rauh O (2021) Distinct lipid bilayer compositions have general and protein-specific effects on K+ channel function. Journal of General Physiology 153 (2): e202012731.

Carvalho‐de‐Souza JL, Saponaro A, Bassetto Jr. CAZ, Rauh O, Schroeder I, Franciolini F, Catacuzzeno L, Bezanilla F, Thiel G, Moroni A (2021) Experimental challenges in ion channel research: uncovering basic principles of permeation and gating in potassium channels. Advances in Physics 5(1): 1978317

Gabriel TS, Hansen U, Urban M, Drexler N, Winterstein T, Rauh O, Thiel G, Kast SM, Schroeder I (2021) Asymmetric interplay between K+ and blocker and atomistic parameters from physiological experiments quantify K+ channel blocker release. Frontiers in Physiology 12: 737834.

Kläsener K, Jellusova J, Andrieux G, Salzer U, Böhler C, Steiner SN, Albinus JB, Cavallari M, Süß B, Voll RE, Boerries M, Wollscheid B, Reth M (2021) CD20 as a gatekeeper of the resting state of human B cells PNAS 118 (7) e2021342118

Langer K, Müller-Längle A, Wempe J, Laube B (2021) Analysis of M4 Transmembrane Segments in NMDA Receptor Function: A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid Modulation. Frontiers in pharmacology 12 769046.

Gallo F, Korsak B, Müller C, Hechler T, Yanakieva D, Avrutina O, Kolmar H, Pahl A (2021) Enhancing the Pharmacokinetics and Antitumor Activity of an a-Amanitin-Based Small-Molecule Drug Conjugate via Conjugation with an Fc Domain, J Med Chem. 64: 4117.

Hamm M, Drossel B (2021) The concerted emergence of well-known spatial and temporal ecological patterns in an evolutionary food web model in space Scientific Reports 11, 1-12.

Khalil A, Rostami P, Auernhammer GK, Andrieu-Brunsen A (2021) Mesoporous Coatings with Simultane-ous Light-Triggered Transition of Water Imbibition and Droplet Coalescence, Adv. Mater. Interfaces, 8, 2100252.

Laucirica G, Terrones YT, Cayóna V, Cortez ML, Toimil-Molares ME, Trautmann C, Marmisollé W, Azzaroni O (2021) Biomimetic Solid-State Nanochannels for Chemical and Biological Sensing Applications Trends in Analytical Chemistry, 144, 116425

Schladt T, Engelmann N, Kubaczka E, Hochberger C and Koeppl H (2021) Automated Design of Robust Genetic Circuits: Structural Variants and Parameter Uncertainty. ACS Synth. Biol. 10, 3316–3329.

Peinetti AS, Lake RJ, Cong W, Cooper L, Wu Y, Ma Y, Pawel GT, Toimil-Molares ME, Trautmann C, Rong L, Marinas B, Azzaroni O, Lu Y (2021) Direct detection of human adenovirus or SARS-CoV-2 with ability to inform infectivity using DNA aptamer-nanopore sensors. Sci Adv 7, eabh2848.

Gräwe A, Ranglack J, Weyrich A and Stein, V (2021) Synthetic protein switches: Combinatorial linker engineering with iFLinkC. Methods Enzymol. 647, 231–255.

Gräwe A and Stein V (2021) Linker Engineering in the Context of Synthetic Protein Switches and Sensors. Trends in Biotechnology 39, 731–744.

Elter A, Yanakieva D, Fiebig D, Hallstein K, Becker S, Betz U, and Kolmar H (2021) Protease-Activation of Fc-Masked Therapeutic Antibodies to Alleviate Off-Tumor Cytotoxicity. Front. Immunol. 12, 715719.

Winterstein, LM, Kukovetz K, Hansen, UP, Schroeder I, Van Etten JL, Moroni A, Thiel G, Rauh O (2021) Distinct lipid bilayer compositions have general and protein-specific effects on K+ channel function. J. Gen. Physiol. 153.

Gerasymenko I, Sheludko YV, Fuertes IN, Schmidts V, Steinel L, Haumann E, Warzecha H (2021) Engineering of a Plant Isoprenyl Diphosphate Synthase for Development of Irregular Coupling Activity ChemBioChem 23(1) e202100465

Schmidt M, Schroeder I, Bauer D, Thiel G, Hamacher K (2021) Inferring functional units in ion channel pores via relative entropy Eur Biophys. J., 50:37-57

Mathony J, and Niopek D (2021) Enlightening Allostery: Designing Switchable Proteins by Photoreceptor Fusion. Adv Biol (Weinh) 5, e2000181.

Güllülü O, Hehlgans S, Mayer B, Gößner I, Petraki C, Hoffmann M, Dombrowsky M, Kunzmann P, Hamacher K, Strebhardt K, Fokas E, Rödel C, Münch F, Rödel F (2021) A spatial and functional interaction of a heterotetramer Survivin-DNA-PKcs complex in DNA damage response Cancer Research 81:2304-17

Bolze H, Riewe L, Bunjes H, Dietzel A, Burg T (2021) Continuous Production of Lipid Nanoparticles by Ultrasound-Assisted Microfluidic Antisolvent Precipitation Chemical Engineering & Technology 44(9):1641-1650

Lehr FX, Kuzembayeva A, Bailey ME, Kleindienst W, Kabisch J, Koeppl H (2021) Functionalizing Cell-Free Systems with CRISPR-Associated Proteins: Application to RNA-Based Circuit Engineering ACS Synthetic Biology

Hoffmann MD; Mathony J, Upmeier zu Belzen J, Hartevald Z, Aschenbrenner S, Stengl C, Grimm D, Correira BE, Eils R, Niopek D (2021) Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein Nucleic Acids Research 49(5) e29

Rauh O, Kukovetz K, Winterstein L, Introini B, Thiel G (2021) Combining in vitro translation with nanodisc technology and functional reconstitution of channels in planar lipid bilayers Methods in Enzymology 652:293-318

Bogen JP, Carrara SY, Fiebig D, Grzeschik J, Hock B, Kolmar H (2021) Design of a Trispecific Checkpoint Inhibitor and Natural Killer Cell Engager Based on a 2 + 1 Common Light Chain Antibody Architecture Front Immunol 12:669496

Liebich VJ, Avrutina O, Habermann J, Hillscher LM, Langhans M, Meckel T, Biesalski M, Kolmar H (2021) Toward Fabrication of Bioactive Papers: Covalent Immobilization of Peptides and Proteins Biomacromolecules 22(7):2954-2962

Saponaro A, Bauer D, Giese H, Swuec P, Porro A, Gasparri F, Sharifzadeh AS, Chaves-Sanjuan A, Alberio L, Parisi G, Cerutti G, Clarke OB, Hamacher K, Colecraft HM, Mancia F. Hendrickson WA, Siegelbaum SA, DiFrancesco D, Bolognesi M, Thiel G, Santoro B, Moroni A (2021) Gating movements and ion permeation in HCN4 pacemaker channels Molecular Cell 81(14):2929-2943

Kaiser C, Schneider J, Groher F, Suess B, Wachtveitl J (2021) What defines a synthetic riboswitch? – Conformational dynamics of ciprofloxacin aptamers with similar binding affinities but varying regulatory potentials Nucleic Acids Research 49(7):3661-3671

Born J, Weitzel K, Suess B, Pfeifer F (2021) A Synthetic Riboswitch to Regulate Haloarchaeal Gene Expression Front Microbiol 12:696181

Worring A, Mayer BE, Hamacher K (2021) Genetic algorithm niching by (Quasi-)infinite memory GECCO '21: Proceedings of the Genetic and Evolutionary Computation Conference 296–304

Prangemaier T, Reich C, Wildner C, Koeppl H (2021) Multi-StyleGAN: Towards Image-Based Simulation of Time-Lapse Live-Cell Microscopy Medical Image Computing and Computer Assisted Intervention (MICCAI)

Karava M, Gockel P, Kabisch J (2021) Bacillus subtilis spore surface display of photodecarboxylase for the transformation of lipids to hydrocarbons Sustainable Energy Fuels 5:1727-1733

Ensinger W (2021) A New Generation of Biomolecular Sensors Based on Polymeric Ion Conducting Nanopores for Medical Diagnostics (wird in neuem Tab geöffnet)Proceedings of the 6th World Congress on Recent Advances in Nanotechnology (RAN'21) Paper No. NDDTE 106

Nasir S, Ali M, Ramirez P, Froehlich K, Cervera J, Mafe S, Ensinger W (2021) Ionic conduction through single-pore and multipore polymer membranes in aprotic organic electrolytes Journal of Membrane Science 635:119505

Duznovic I, Gräwe A, Weber W, Müller LK, Ali M, Ensinger W, Tietze A, Stein V (2021) Ultrasensitive and Selective Protein Recognition with Nanobody-Functionalized Synthetic Nanopores Small 2101066

Glinkowska M, Waldminghaus T, Riber L (2021) Editorial: Bacterial Chromosomes Under Changing Environmental Conditions Front Microbiol 12:633466

Zimmermann M, Nguyen M, Schultheiss CM; Kolmar H, Zimmer A (2021) Use of 5-Thio-L-Fucose to modulate binding affinity of therapeutic proteins Biotechnology and Bioengineering 118(5):1818-1831

John D, Stanzel M, Andrieu-Brunsen A (2021) Surface Plasmons and Visible Light Iniferter Initiated Polymerization for Nanolocal Functionalization of Mesoporous Separation Layers Advanced Functional Materials 31(20):2009732

Hillscher LM, Liebich VJ, Avrutina O, Biesalski M, Kolmar H (2021) Functional paper-based materials for diagnostics ChemTexts 7(14)

Izdebska-Podsiadly J, Dörsam E (2021) Storage stability of the oxygen plasma-modified PLA film Bulletin of Material Science 44(79)

Elter A, Bock T, Spiehl D, Russo G, Hinz SC, Bitsch S, Baum E, Langhans M, Meckel T, Dörsam E, Kolmar H, Schwall G (2021) Carbohydrate binding module-fused antibodies improve the performance of cellulose-based lateral flow immunoassays Scientific Reports 11(7880)

Schmidt M, Hamacher K (2021) Identification of biophysical interaction patterns in direct coupling analysis Phys. Rev. E 103, 042418

Ramirez P, Prerz-Grau JJ, Cervera J, Nasir S, Ali M, Ensinger W, Mafe S (2021) Negative differential resistance and threshold-switching in conical nanopores with KF solutions Appl Phys Lett 118:181903

Baumann L, Bruder S, Kabisch J, Boles E, Oreb M (2021) High-Throughput Screening of an Octanoic Acid Producer Strain Library Enables Detection of New Targets for Increasing Titers in Saccharomyces cerevisiae ACS Synth Biol 10(5):1077-1086

Carrara SC, Fiebig D, Bogen JP, Grzeschik J, Hock B, Kolmar H (2021) Recombinant Antibody Production Using a Dual-Promoter Single Plasmid System Antibodies 10(2):18

Engel AJ, Kithil M, Langhans M, Rauh O, Cartolano M, van Etten JL, Moroni A, Thiel G (2021) Codon Bias Can Determine Sorting of a Potassium Channel Protein Cells 10(5):1128

Ulrich N, Spende A, Burr L, Sobel N, Schubert I, Hess C, Trautmann C, Toimil-Molares ME (2021) Conical Nanotubes Synthesized by Atomic Layer Deposition in Etched Ion-Track Nanochannels Nanomaterials 11, 1874;

2020

Kukovetz K, Hertel B, Schvarcz CR, Saponaro A, Manthey M, Burk U, Greiner T, Steward GF, Van Etten JL, Moroni A, Thiel G, Rauh O (2020) A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae. Viruses 12(10):1107.

Aschenbrenner S, Kallenberger S, Hoffmann MD, Huck A, Eils R, Niopek D (2020) Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity. Sci Adv 6(6):eaay018

Benary M, Bohn S, Lüthen M, Nolis IK, Blüthgen N, Loewer A (2020) Disentangling Pro-mitotic Signaling during Cell Cycle Progression using Time-Resolved Single-Cell Imaging. Cell Reports 31, 107514.

Engelmann N, Linzner D, Koeppl H (2020) Continuous-time Bayesian networks with clocks. Proceedings of the 37th International Conference on Machine Learning (ICML), 119:2912-2921.

Macarrón Palacios A, Grzeschik J, Deweid L, Krah S, Zielonka S, Rösner T, Peipp M, Valerius T, Kolmar H (2020) Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies, Front Immunol., 11: 560244.

Drossel B (2020) What condensed matter physics and statistical physics teach us about the limits of unitary time evolution. Quantum Studies: Mathematics and Foundations 7, 217-231.

Khalil A, Zimmermann M, Bell AK, Kunz U, Hardt S, Kleebe HJ, Stark RW, Stephan P, Andrieu-Brunsen A (2020) Insights into the interplay of wetting and transport in mesoporous silica films J. Colloid Interf. Sci., 560, 369.

Brilmayer R, Kübelbeck S, Khalil A, Brodrecht M, Kunz U, Kleebe HJ, Buntkowsky G, Baier G, Andrieu-Brunsen A (2020) Influence of nanoconfinement on the pKa of polyelectrolyte functionalized silica mesopores, Adv. Mat. Interf., 1901914.

Konrath F, Mittermeier A, Cristiano E, Wolf J and Loewer A (2020) A systematic approach to decipher crosstalk in the p53 signaling pathway using single cell dynamics. PLoS Comput. Biol. 16, e1007901.

Gräwe A., Ranglack J, Weber W and Stein V (2020a) Engineering artificial signalling functions with proteases. Current Opinion in Biotechnology 63, 1–7.

Zimmermann M, Kolmar H, Zimmer A (2020) S-Sulfocysteine – Investigation of cellular uptake in CHO cells Journal of Biotechnology 335:27-38

Fritschen A, Blaeser A (2020) Biosynthetic, biomimetic, and self-assembled vascularized Organ-on-a-Chip systems Biomaterials 268:120556

Engel AJ, Winterstein L, Kithil M, Langhans M, Moroni A, Thiel G (2020) Light-Regulated Transcription of a Mitochondrial-Targeted K+ Channel Cells 9(11):2507

Mathony J, Niopek D (2020) Enlightening Allostery: Designing Switchable Proteins by Photoreceptor Fusion Advanced Biology 5(5):2000181

Brilmayer R, Förster C, Zhao L, Andrieu-Brunsen A (2020) Recent trends in nanopore polymer functionalization Current Opinion in Biotechnology 63:200-209

Sozhamannan S, Waldminghaus T (2020) Exception to the exception rule: synthetic and naturally occurring single chromosome Vibrio cholerae Environmental Microbiology 22(10):4123-4132

Wilkens D, Meusinger R, Hein S, Simon J (2020) Sequence analysis and specificity of distinct types of menaquinone methyltransferases indicate the widespread potential of methylmenaquinone production in bacteria and archaea Environmental Microbiology 23(3):1407-1421

Hoff J, Daniel B, Stukenberg D, Thuonyi BW, Waldminghaus T, Fritz G (2020) Vibrio natriegens: an ultrafast-growing marine bacterium as emerging synthetic biology chassis Environmental Microbiology 22(10):4394-4408

Mathony J, Harteveld Z, Schmelas C, Upmeier Zu Belzen J, Aschenbrenner S, Sun W, Hoffmann MD, Stengl C, Scheck A, Georgeon S, Rosset S, Wang Y, Grimm D, Eils R, Niopek D (2020) Computational design of anti-CRISPR proteins with improved inhibition potency. Nat. Chem. Biol. 16, 725–730.

Doçi G, Fuchs L, Kharbanda Y, Schickling P, Zulkower V, Hillson N, Oberortner E, Swainston N, Kabisch J (2020) DNA Scanner: a web application for comparing DNA synthesis feasibility, price, and turnaround time across vendors Synthetic Biology, ysaa011, https://doi.org/10.1093/synbio/ysaa011

Li Y, Rehbock C, Nachev M, Stamm J, Sures B, Blaeser A, Barcikowski S (2020) Matrix-specific mechanism of Fe ion release from laser-generated 3D-printable nanoparticle-polymer composites and their protein adsorption properties Nanotechnology 31(40):405703. doi: 10.1088/1361-6528/ab94da

Schäfer B, Emonts C, Glimpel N, Ruhl T, Obrecht AS, Jockenhoevel S, Gries T, Beier JP, Blaeser A (2020) Warp-Knitted Spacer Fabrics: A Versatile Platform to Generate Fiber-Reinforced Hydrogels for 3D Tissue Engineering Materials (Basel) 13(16):E3518. doi: 10.3390/ma13163518

Kunzmann, P.,Mayer, B.E. Hamacher, K. (2020) Substitution matrix based color schemes for sequence alignment visualization BMC Bioinformatics 21(209)

Brunner JD, Jakob RP, Schulze T, Neldner Y, Moroni A, Thiel G, Maier S, Schenck S (2020) Structural basis for ion selectivity in TMEM175 K+ channels eLIFE

Herzog N, Hübner H, Rüttiger C, Gallei M, Andrieu-Brunsen A (2020) Functional Metalloblock Copolymers for the Preparation and In Situ Functionalization of Porous Silica Films Langmuir doi.org/10.1021/acs.langmuir.0c00245

Tran MH, Brilmayer R, Liu L, Zhuang HL, Hess C, Andrieu-Brunsen A, Birkel CS (2020) Synthesis of a Smart Hybrid MXene with Switchable Conductivity for Temperature Sensing ACS Appl. Nano Mater

Prangemeier T, Lehr F, Schoeman RM, Koeppl H (2020) Microfluidic platforms for the dynamic characterisation of synthetic circuitry Current Opinion in Biotechnology 63:167-176

Müller LK, Duznovic I, Tietze D, Weber W, Ali M, Stein V, Ensinger W, Tietze A (2020) Ultrasensitive and selective copper (II) detection: introducing a bioinspired and robust sensor Chem. Eur. J. 10.1002/chem.202001160

Bernhard M, Diefenbach M, Biesalski M, Laube B (2020) Electrical Sensing of Phosphonates by Functional Coupling of Phosphonate Binding Protein PhnD to Solid-State Nanopores ACS Sens 5(1) 234-241

Ochs M, Maohammadi R, Vogel N, Andrieu-Brunsen A (2020) Wetting‐Controlled Localized Placement of Surface Functionalities within Nanopore Small 1906463

Grau FX, Jaeger J, Groher F, Suess B, Muller YA (2020) The complex formed between a synthetic RNA aptamer and the transcription repressor TetR is a structural and functional twin of the operator DNA–TetR regulator complex Nucleic Acids Research, gkaa083

Gräwe A, Ranglack J, Weyrich A, Stein V (2020) iFLinkC: an iterative functional linker cloning strategy for the combinatorial assembly and recombination of linker peptides with functional domains Nucleic Acids Research, gkz1210, https://doi.org/10.1093/nar/gkz1210

Sheludko YV, Volk J, Brandt W, Warzecha H (2020) Expanding the Diversity of Plant Monoterpenoid Indole Alkaloids Employing Human Cytochrome P450 3A4 ChemBioChem 21(14):1976-1980

Engel F, Ossipova E, Jakobsen P-J, Vockenhuber M-P, Suess B (2020) sRNA scr5239 Involved in Feedback Loop Regulation of Streptomyces coelicolor Central Metabolism Front Microbiol 10:3121

Jenewein T, Kanner SA, Bauer D, Hertel B, Colecraft HM; Moroni A, Thiel G, Kauferstein S (2020) The mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency Channels 14(1):163-174

Baalmann M, Neises L, Bitsch S, Schneider H, Deweid L, Werther P, Ilkenhans N, Wolfring M, Ziegler MJ, Wilhelm J, Kolmar H, Wombacher R (2020) A Bioorthogonal Click Chemistry Toolbox for Targeted Synthesis of Branched and Well-Defined Protein–Protein Conjugates Angewandte Chemie International Edition 59(31):12885-12839

Sperlea T, Muth L, Martin R, Weigel C, Waldminghaus T, Heider D (2020) gammaBOriS: Identification and Taxonomic Classification of Origins of Replication in Gammaproteobacteria using Motif-based Machine Learning Scientific Reports 10:6727

Söhling N, Neijhoft J, Nienhaus V, Acker V, Harbig J, Menz F, Ochs J, Verboket RD, Ritz U, Blaeser A, Dörsam E, Frank J, Marzi I, Henrich D (2020) 3D-Printing of Hierarchically Designed and Osteoconductive Bone Tissue Engineering Scaffolds Materials 13(8):1836

Duarte Campas DF, Lindsay CD, Roth JG, LeSavage BL, Seymour AJ, Krajina BA, Ribeiro R, Costa PF, Blaeser A, Heilshorn SC (2020) Bioprinting Cell- and Spheroid-Laden Protein-Engineered Hydrogels as Tissue-on-Chip Platforms Front Bioeng Biotechnol 8:374

Basavarajappa D, Uebbing S, Kreiss M, Lukic A, Suess B, Steinhilber D, Samuelsson B, Rådmark O (2020) Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells PNAS 117(15):8573-8583

Murry CR, Agarkova IV, Ghosh JS, Fitzgerald FC, Carlson RM, Hertel B, Kukovetz K, Rauh O, Thiel G, Van Etten JL (2020) Genetic Diversity of Potassium Ion Channel Proteins Encoded by Chloroviruses That Infect Chlorella heliozoae Viruses 12(6):678

Tran NT, Kaldenhoff R (2020) Metabolic engineering of ketocarotenoids biosynthetic pathway in Chlamydomonas reinhardtii strain CC-4102 Scientific Reports 10(1):10688

Yanakieva D, Elter A, Bratsch J, Friedrich K, Becker S, Kolmar H (2020) FACS-Based Functional Protein Screening via Microfluidic Co-encapsulation of Yeast Secretor and Mammalian Reporter Cells Scientific reports 10:10182

Fröhlich K, Nasir S, Ali M, Ramirez P, Cervera J, Mafe S, Ensinger W (2020) Fabrication of soft-etched nanoporous polyimide membranes for ionic conduction and discrimination Materials 617:118633

Sinzinger M, Gehri M, Koeppl H (2020) Poisson channel with binary Markov input and average sojourn time constraint S. 2873-2878, ISIT'20 – International Symposium on Information Theory, virtual online conference, 21.-26. June 2020, ISBN 978-1-7281-6433-5

Bogen JP, Storka J, Yanakieva D,Fiebig D, Grzeschik J, Hock B, Kolmar H (2020) Isolation of Common Light Chain Antibodies from Immunized Chickens Using Yeast Biopanning and Fluorescence-Activated Cell Sorting Biotechnology Journal 16(3):2000240

Sauer HM, Braig F, Dörsam E (2020) Leveling and Drying Dynamics of Printed Liquid Films of Organic Semiconductor Solutions in OLED/OPV Applications Advanced Materials Technologies 6(2):2000160

Prangemeier T, Reich C, Koeppl H (2020) Attention-Based Transformers for Instance Segmentation of Cells in Microstructures (wird in neuem Tab geöffnet) IEEE, International Conference on Computational Intelligence in Bioinformatics and Computational Biology, virtual Conference, October 27-29

Prangemeier T, Wildner C, Francani AO, Reich C, Koeppl H (2020) Multiclass Yeast Segmentation in Microstructured Environments with Deep Learning (wird in neuem Tab geöffnet) IEEE, International Conference on Computational Intelligence in Bioinformatics and Computational Biology, virtual Conference, October 27-29

Busche JF, Möller S, Klein A-K, Stehr M, Purr F, Bassu M, Burg TP, Dietzel A (2020) Nanofluidic Immobilization and Growth Detection of Escherichia coli in a Chip for Antibiotic Susceptibility Testing Biosensors 10(10):135

Bernhard M, Laube B (2020) Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs Scientific Reports 10:16569

Ulitzka M, Carrara S, Grzeschik J, Kornmann H, Hock B, Kolmar H (2020) Engineering therapeutic antibodies for patient safety: tackling the immunogenicity problem Protein Engineering, Design and Selection 33:gzaa025

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