Verstehen und Bauen von Ionenkanälen

Im Rahmen des Symposiums werden aktuelle Erkenntnisse über Struktur-Funktionsbeziehungen von Ionenkanalproteinen aus experimentellen und computergestützten Studien sowie Konzepte zur Nutzung dieser Informationen für das Design synthetischer Kanalproteine vorgestellt.

Freitag, 8. September 2023 13 – 20 Uhr

Samstag, 9. September 2023 10 – 20 Uhr

Bio-Campus

Schnittspahnstraße 3

Programm

Freitag 8. September 2023

Session 1
Chair: Anna Moroni
13:00 – 13:30 Udi Isacoff
Do-Si-Do of NMDA receptor activation
13:30 – 13:50 Viktor Stein
Of sensors and nanopores
13:50 – 14:10 Wolfgang Ensinger
Towards application: biomimetic nanopores in plastic
14:10 – 14:40 Coffee break
Session 2
Chair: Katjusa Brejc
14:40 – 15:10 Yoshihiro Kubo
A novel ion conducting route
15:10 – 15:30 Eitan Reuveny
Calcium signaling beyond the cellular level
15:30 – 16:15 Coffee Break
Session 3
Chair: Peter Hansen
16:15 – 16:45 Crina Nimigean
Lipid modulation in ion channels
16:45 – 17:15 Andrea Saponaro
Structural determinant of the ivabradine-induced block of pacemaker hcn channels
17:15 – 17:30 Dario DiFrancesco
Gerhard Thiel and the German-Italian connection:
peeking into a microscopic view of early data
17:30 – 18:00 Drink
18:00 – 18:30 Boris Martinac
Piezo1 and TRPM4 ion channels drive left ventricular hypertrophy in response to pressure overload

Samstag 9. September 2023

Session 4
Chair: Massimo Zeviani
9:30 – 9:55 Robert Zorec
From lysosomal fusion to treating prostate cancer by immunohybridomas
9:55 – 10:20 Mike Blatt
How to you get stomata to shut up
10:20 – 10:40 Antonio Zaza
The puzzling relationship between PLN mutations and cardiac dysfunction
10:40 – 11:10 Coffee break
Session 5
Chair: Uli Kubitschek
11:10 – 11:35 Alessio Arcadi
Structural basis of pH-dependent activation in a CLC transporter
11:35 – 12:00 Michael Pusch
Water dissociation underlying pH dependence of CLC-0?
12:00 – 12:10 Andrea Brüggemann
20 years of automated patch clamping
12:10 – 13:10 Lunch
Session 6
Chair: Fillipo Manchia
13:10 – 13:40 Eduardo Peroso
Jellyfish stinging as a model for auditory mechanotransduction
13:40 – 14:00 Oliver Rauh
Mutual interplay between filter gate and Ba2+ block in the potassium channel pore
14:00 – 14:30 Henry Colecraft
A tale of two queens
14:30 – 15:20 Coffee Break
Session 7
Chair: Adam Bertl
15:20 – 15:50 Simon Scheuring
Four! Four no more!
15:50 – 16:10 Indra Schröder
Regulation of the K+ selectivity filter gate in the minimal Kcv channel
16:10 – 16:30 Christine Gibhardt
Redox regulation of calcium signaling
16:30 – 16:50 Jim Van Etten
Chloroviruses, Nebraska, Darmstadt and Milano
16:50 – 17:30 Coffee Break
17:30 – 18:00 Dan Minor
A structural view of how channels become channels
18:00 – open end Dinner (Botanical Garden)

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