Within the ERC project CONSYN “Contextualizing Biomolecular Circuits Models for Synthetic Biology” the Koeppl Lab at Technische Universität Darmstadt, Germany invites applications, starting as soon as possible for a:

PhD Position – Synthetic Biology

initially limited for 3 years, with the possibility to extend.

CONSYN aims to discover general design principles for synthetic genetic circuits with the help of computational analysis and provides experimental characterization methods on the single-cell level for synthetic biology. In collaboration with computational people within CONSYN, different synthetic circuits will be evaluated in a cell-free in-vitro setting and in-vivo based on the model organisms E. coli and Saccharomyces cerevisiae.

The PhD student will work on the in-vitro and in-vivo implementation, analysis and optimization of synthetic circuits. Novel methods based on microfluidics and fluorescent microscopy will be developed to characterize the dynamic response profile of synthetic circuits. The student can resort to already established technology within the Koeppl Lab, such as microfluidic systems to run cell-free reactions at steady state conditions, droplet-based microfluidics to study cell-free reactions in batch mode and microfluidic single-cell traps to accurately track and quantify single cells. Engaging into joint theoretical and experimental work within the Koeppl Lab is highly encouraged.

Technische Universität Darmstadt provides the environment and support for publishing and presenting original research results at leading international conferences and in scientific journals. The opportunity for the preparation of a doctoral thesis will be given. The fulfillment of the research and service requirements attached to this employment will equate to the academic requirements for the candidate's doctoral degree.

Your profile:

  • Completed studies (M.Sc or comparable) in biology, biochemistry, biophysics, biotechnology or equivalent
  • Wet-lab experience, in particular genetic engineering
  • Interested to work in the field of synthetic biology
  • Appreciation for interdisciplinary work and proactive drive to collaborate with computational people


Your application must include

  • a cover letter explaining succinctly why you are interested in this position and why you believe you are the right candidate
  • a CV
  • a list of passed courses and obtained grades
  • contact details of at least two references (academic advisors) of yours

Opportunity for further qualification (doctoral dissertation) is given. The fulfillment of the duties likewise enables the scientific qualifications of the candidate.

The Technische Universität Darmstadt intends to increase the number of female employees and encourages female candidates to apply. In case of equal qualifications applicants with a degree of disability of at least 50 or equal will be given preference. Wages and salaries are according to the collective agreements on salary scales, which apply to the Technische Universität Darmstadt (TV-TU Darmstadt). Part-time employment is generally possible.


Prof. Heinz Koeppl, Rundeturmstrasse 12, 64283 Darmstadt, heinz.koeppl@bcs.tu-darmstadt.de

Please send your documents as one single PDF file to: office@bcs.tu-darmstadt.de indicating the application code number within the subject line. Incomplete applications and applications in different file formats will be discarded.

Code No. 712

Published on

November 28, 2019

Application deadline

January 10, 2020