The ProLOEWE-Escape Room “Mars Mission“ was one of the many events at this year's Open Campus @TU Darmstadt. The mission: The Mars station’s AI is going crazy and threatens to destroy the Earth. Only the emergency stop button can help now, but the box containing the button is locked. To get the key, puzzle pieces need to be found and put together, secret symbols on agar plates must be deciphered and electronic locks have to be cracked. Lots of fun, not just for science nerds, which requires teamwork. The Escape room was designed in 2022 by the three LOEWE projects ALLEGRO, SMolBits (University of Kassel) and FLOW FOR LIFE (TU Darmstadt) in cooperation with the Centre for Synthetic Biology (TU Darmstadt). Special thanks to Dr. Melanie Mikosch-Wersching from the Centre for Synthetic Biology and Mrs. Michaela Becker-Röck from FLOW FOR LIFE for organizing this event.