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DAAD GSSP Scholarships

Scholarships for international PhD students

The Graduate School Life Science Engineering (GS LSE) at the Technical University Darmstadt was selected by the Graduate School Scholarship Programme (GSSP) of the German Academic Exchange Service (DAAD) to nominate and host up to 4 international PhD students in 2023 and 2024 (two each year). Two scholarships are available for doctoral studies to begin May – December 2023 (applications accepted 15st October – 15st December 2022). Please note that each DAAD scholarship in this programme comprises funding for up to three years. Extension to a fourth year may be possible in very well founded cases.

International applicants who have not been living in Germany for more than 15 months can apply. At the time of the application, the last final exam (Master Degree) should have taken place no longer than six years ago.

Candidates are selected in a multi-step process by the Graduate School Life Science Engineering and the DAAD. Candidates are nominated by the graduate school and the final decision is made by the DAAD.

Applications will be reviewed by a selection committee of PIs at the Graduate School Life Science Engineering. Based on the excellence of their applications, candidates will be selected for a nomination to the final decision process of DAAD.

The applicants who have been selected for a scholarship must further submit a completed application form with all supporting documents via the DAAD-portal https://www.meindaad.de.

Successful applicants will be offered a full PhD scholarship, financed by the GSSP programme of the DAAD.

The candidates will have the opportunity to undertake their doctoral studies under the supervision of one scientist within the Graduate School Life Science Engineering.

Note the starting dates are dependent on the application and visa process, please review the steps linked above and plan ahead.

Scientific Part

The gain in knowledge in basic research in the field of the life sciences has been rapid and has opened up the possibility of using principles of engineering not only to design and produce chemical and biological molecules that cover a broad spectrum of research and applications, but also to intervene in cells, cell populations and organisms to meet predefined requirements in terms of function, regulation or multidimensional behavior of the entire ensemble. Synthetic biology in particular describes the engineering approach to endow biological cells with new molecular functionality. Unlike traditional biotechnology, it follows the principle of achieving this functionality through the composition of individual, well-characterized, standardized molecular components.

The Graduate School LSE is a central scientific institution of the Technical University Darmstadt and pursues the goal of establishing interdisciplinary research and training of excellent international doctoral students at the interface between engineering sciences and life sciences.

At the Technical University Darmstadt, we see as potentially belonging to the Graduate School of Life Science Engineering those who

(1) want to understand biological systems in their functional details, regardless of their level of complexity, and

(2) apply the acquired knowledge and intervene in biological systems in a targeted manner according to rational design principles, regardless of the size and complexity scales, or apply knowledge about the function of biological systems for the development of bio-inspired active substances, materials, machines or processes.

The Technical University Darmstadt stands for interdisciplinary research. Particularly in the field of life science engineering, Technische Universität Darmstadt is visible nationally and internationally in the form of individual research projects and within the framework of research cooperations.

The following are examples of application areas and research groups at the Technical University Darmstadt that are identified in the field of Life Science Engineering:

Prof. Dr. Heinz Koeppl, Department of Electrical Engineering and Information Technology, Department of Biology: The group specializes on genetic circuit design in synthetic biology. Computational and experimental methods to rationally construct circuits in cell-free, bacterial and mammalian systems are developed.

Prof. Dr. Harald Kolmar, Applied Biochemistry: The group is specialized in protein engineering with a focus on antibody engineering. We optimize enzymes and antibodies with respect to their stability or selectivity and endow them with tailor-made functional properties.

Prof. Dr. Cristina Cardoso, Cell biology & epigenetics: We develop and apply chromatin/epigenetic engineering approaches to understand and for targeted manipulation of cellular proliferation, differentiation and reprogramming in mammalian systems.

Prof. Dr. Barbara Drossel, Theory of Complex Systems: We use mathematical modeling and computer simulations to explore the functioning, evolution, and response to environmental conditions of biological networks.

Written applications as one single pdf are to be submitted with the usual documents including a CV, a motivational letter, names and contact data of at least 2 references and the Project of choice to .

PhD position in allosteric GPCR ligand drug discovery

Topic: Identifying positive allosteric modulators of G-protein-coupled receptors using proximity-assisted screening

Aim: Develop multifunctional dendimer linkers and use them to identify ligands for GPCRs that can enhance the signalling of endogeous agonists. This will allow a much more refined pharmacology for diseaes such as depression, pain etc.

Where: Technical University Darmstadt, Institute of Organic Chemistry and Biochemistry

Suited for: PhD candidates interested in chemical biology and the application to drug discovery

Requirements: Master in life sciences or chemistry, first experiences in cell biology is a plus

We offer: Training in cutting-edge drug discovery techniques and dedicated mentoring in an interdisciplinary and lively group. The project is scheduled 3 years and paid according to a E13/2 salary.

Mentor & further infos: Prof. Felix Hausch https://www.chemie.tu-darmstadt.de/hausch/rg_hausch/index.en.jsp

PhD position in protein-protein interaction studies

Topic: Identifying chemical-induced protein-protein interactions by high-throughput, site-specific, in-cell photo-crosslinking

Aim: Develop a protocol for covalent affinity capturing of photocrosslinked proteins, followed by mass spectrometry and molecular biological characterization of the identified proteins.

The method is exemplified for the FK506-binding protein 12 (FKBP12), the leading model system for molecular glues.

Where: Technical University Darmstadt, Institute of Organic Chemistry and Biochemistry

Suited for: PhD candidates interested in biochemistry, molecular & chemical biology and the application to drug discovery

Requirements: Master in life sciences or chemistry with a solid background in protein biochemistry techniques

We offer: Training in cutting-edge drug discovery techniques and dedicated mentoring in an interdisciplinary and lively group. The project is scheduled 3 years and paid according to a E13/2 salary.

Mentor & further infos: Prof. Felix Hausch https://www.chemie.tu-darmstadt.de/hausch/rg_hausch/index.en.jsp

PhD position in computational methods in the natural sciences

The Hamacher group at Technische Universität Darmstadt invites applications for the position of a Research Assistant/Ph.D. Student (all genders) – 50% at first term of 3 years.

The research group focus on computational methods in the natural sciences, especially mathematical and algorithmic aspects. Research topics include but are not limited to:

* machine learning

* statistical physics

* heuristic optimization, genetic and evolutionary programming

Ideally, you have a completed university degree (Master, Diploma) with a background in one or more of relevant areas (physics, computer science, bioinformatics, mathematics). The fulfillment of the duties likewise enables the scientific qualifications of the candidate. The scope and field of the Ph.D. research is to be discussed, but the Ph.D. program can be chosen from the departments of physics, computer science, or biology. The Technische Universität Darmstadt intends to increase the number of female employees and encourages female candidates to apply. In case of equal qualifications applicants with a degree of disability of at least 50 or equal will be given preference. Wages and salaries are according to the collective agreements on salary scales, which apply to the Technische Universität Darmstadt (TV-TU Darmstadt).

By submitting your application, you agree that your data may be stored and processed for the purpose of filling the vacancy. You can find our privacy policy on our webpage.

Please address your applications, including your certificates, to Prof. Dr. Kay Hamacher, TU Darmstadt, Schnittspahnstr. 10, 64287 Darmstadt, or via email (only pdf format acceptable, only one file) to:

PhD position in Stem Cell and Developmental Biology

The Biology Department of the TU Darmstadt (Technical University of Darmstadt), Germany, invites applications for a PhD position in the Stem Cell and Developmental Biology group. The appointment is for three years.

Three-dimensional tissue- or organ-like cell cultures produced in the laboratory are promising alternatives that allow for efficacy and toxicity tests on human cells outside the body. They could also be of interest for regenerative medicine in the future. However, the quality of organ-like cell cultures on a centimeter scale is currently not yet sufficient. In particular, there is a lack of a vascular system that supports the maintenance, growth and maturation of cell in such cultures.

We are looking for a highly motivated and creative person who is interested in working on the generation of vascularized tissue- or organ-like cell cultures.

https://www.bio.tu-darmstadt.de/forschung/ressearch_groups/Nuber_Start.en.jsp

www.tu-darmstadt.de/flowforlife

The project serves the scientific qualification of the applicant leading to a PhD degree.

Required qualifications and experience

A Master degree in a relevant field (e.g. biology, biotechnology, molecular medicine, biochemistry).

Very good molecular methods/biochemistry skills and cell culture experience.

Strong ambition to develop into an independent scientist.

Excellent communication, organizational and interpersonal skills.

Very good English language skills.

We offer an open and supportive academic environment with the possibility to work on cutting edge research projects. Post-doctoral scientists and technical assistants are present in our group that provide an excellent scientific and technical support for your research. We use a wide spectrum of methods: molecular cloning techniques, primary and iPS cell culture, animal models, biochemistry, gene expression analyses, FACS, cell-based assays, genome editing by the CRISPR/Cas system, viral-based gene delivery, immunocyto- and histochemistry, in situ hybridization, light, epifluorescence and confocal microscopy.

The TU Darmstadt is a family-friendly university, intends to increase the number of female faculty members and particularly encourages female candidates to apply. In case of equal qualifications applicants with a degree of disability of at least 50 or equal will be given preference. Wages and salaries are according to the collective agreements on salary scales, which apply to the TU Darmstadt (TV-TU Darmstadt).

Highly motivated and enthusiastic candidates who enjoy working in a team and contribute to a supportive working atmosphere are invited to send an application including CV, certificates, and names of 2-3 reference persons to .